60 days in South America, Central America & Mexico Itinerary

60 days in South America, Central America & Mexico Itinerary

Make it your trip
Fly
1
Tigre, Argentina
— 31 nights
Fly
2
Villa La Angostura, Argentina
— 7 nights
Bus
3
Perito Moreno, Argentina
— 5 nights
Drive
4
Puerto Natales (Torres del Paine), Chile
Fly
5
San Pedro de Atacama, Chile
— 2 nights
Fly
6
Cusco, Peru
— 2 nights
Fly to Mariscal Sucre International Airport, Drive to Puerto Quito
7
Puerto Quito, Ecuador
— 1 night
Drive to Mariscal Sucre International Airport, Fly to Cartagena
8
Cartagena, Colombia
— 1 night
Fly
9
Guatemala City, Guatemala
— 2 nights
Fly
10
San Miguel de Allende, Mexico
— 2 nights

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Tigre, Argentina — 31 nights

Teeming with weekend visitors and day-trippers from the national capital, Tigre and its lush nature offer a range of opportunities for exploring the great outdoors.
Venture out of the city with trips to San Antonio de Areco (Puente Viejo, Museo Gauchesco y Parque Criollo Ricardo Guiraldes, &more), Lujan (Museos & Cripta Basilica Nuestra Senora De Lujan, Basilica de Lujan, &more) and Vicente Lopez (Paseo de la Costa & Alto Valle Parapente). And it doesn't end there: admire the masterpieces at Museo de arte Tigre, get to know the resident critters at Temaiken Biopark, take in the architecture and atmosphere at Catedral de San Isidro, and contemplate the long history of Villa Ocampo.

For more things to do, reviews, and other tourist information, go to the Tigre vacation planning website.

Sao Paulo, Brazil to Tigre is an approximately 5.5-hour flight. You can also drive; or do a combination of bus and train. In September, Tigre is a bit cooler than Sao Paulo - with highs of 21°C and lows of 11°C. Wrap up your sightseeing on the 16th (Sun) early enough to fly to Villa La Angostura.
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Museums · Historic Sites · Parks · Outdoors
Side Trips

Villa La Angostura, Argentina — 7 nights

A trip to Villa La Angostura leads to the lush "Garden of Patagonia," where the scenic backdrop features pristine forests, lakes, and mountains.
Explore the numerous day-trip ideas around Villa La Angostura: Mirador Lago Traful (in Villa Traful) and San Martin de los Andes (Route of the Seven Lakes, Playa Quila Quina, &more). And it doesn't end there: explore the activities along Rio Correntoso, take in the dramatic scenery at Cascada del Rio Bonito, get outside with Cascada Dora y Santa Ana, and look for gifts at Mamuschka.

To find other places to visit, photos, and other tourist information, go to the Villa La Angostura travel route tool.

Traveling by flight from Tigre to Villa La Angostura takes 4.5 hours. Alternatively, you can drive; or take a bus. Traveling from Tigre in October, you will find days in Villa La Angostura are slightly colder (17°C), and nights are colder (1°C). Finish your sightseeing early on the 23rd (Sun) to allow enough time to take a bus to Perito Moreno.
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Parks · Outdoors · Nature · Scenic Drive
Side Trips

Perito Moreno, Argentina — 5 nights

Perito Moreno is a town in the northwest of Santa Cruz Province, Argentina, 25 km east of Lake Buenos Aires. You'll find plenty of places to visit near Perito Moreno: Los Antiguos (Portal La Ascension, Monte Zeballos, &more). There's more to do: don't miss a visit to Cave of the Hands.

For where to stay, other places to visit, maps, and other tourist information, read our Perito Moreno road trip website.

Take a bus from Villa La Angostura to Perito Moreno in 12.5 hours. Alternatively, you can drive; or do a combination of bus, shuttle, and flight. In October, daily temperatures in Perito Moreno can reach 17°C, while at night they dip to 3°C. You will leave for Puerto Natales (Torres del Paine) on the 29th (Sat).
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Parks · Nature · Outdoors · Scenic Drive
Side Trip
Surrounded by towering mountains, shimmering lakes, and the region's rugged hills, Puerto Natales serves as a bustling jumping-off point for exploring the Torres del Paine National Park.
To see more things to do, photos, maps, and tourist information, read our Puerto Natales (Torres del Paine) trip itinerary maker website.

Getting from Perito Moreno to Puerto Natales (Torres del Paine) by car takes about 12.5 hours. Traveling from Perito Moreno to Puerto Natales (Torres del Paine), you'll gain 1 hour due to the time zone difference. Expect slightly colder weather when traveling from Perito Moreno in October: highs in Puerto Natales (Torres del Paine) hover around 13°C, while lows dip to 6°C. You will leave for San Pedro de Atacama on the 29th (Sat).
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Tours · Outdoors · Wildlife · Parks

San Pedro de Atacama, Chile — 2 nights

Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Go for a jaunt from San Pedro de Atacama to Calama to see Mall Plaza Calama about 1h 25 min away. And it doesn't end there: take in the dramatic natural features at Valle De La Luna, take in the natural beauty of Geyser del Tatio, and explore the ancient world of Pukara de Quitor.

To find where to stay, traveler tips, other places to visit, and tourist information, you can read our San Pedro de Atacama trip maker app.

Traveling by flight from Puerto Natales (Torres del Paine) to San Pedro de Atacama takes 8.5 hours. Alternatively, you can drive; or take a bus. When traveling from Puerto Natales (Torres del Paine) in October, plan for much warmer days and about the same nights in San Pedro de Atacama: temperatures range from 28°C by day to 3°C at night. Finish up your sightseeing early on the 1st (Tue) so you can catch the flight to Cusco.
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Nature · Parks · Historic Sites · Shopping
Side Trip

Cusco, Peru — 2 nights

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Start off your visit on the 2nd (Wed): contemplate the long history of Qorikancha, admire the striking features of Centro Historico De Cusco, then contemplate the long history of Plaza de Armas, then trek along exploor, and finally take in the architecture and atmosphere at Iglesia San Pedro. Here are some ideas for day two: examine the collection at Museo de Arte Precolombino, then contemplate the long history of Sacsayhuaman, and then get engrossed in the history at Museo Inka.

To see ratings, more things to do, other places to visit, and other tourist information, read our Cusco trip planner.

Fly from San Pedro de Atacama to Cusco in 9 hours. Alternatively, you can drive; or take a bus. The time zone changes from Chile Standard Time to Peru Standard Time, which is usually a -1 hour difference. Traveling from San Pedro de Atacama in November, Cusco is a bit warmer at night with lows of 8°C. Wrap up your sightseeing on the 3rd (Thu) to allow time to travel to Puerto Quito.
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Historic Sites · Museums · Outdoors · Trails

Puerto Quito, Ecuador — 1 night

Puerto Quito is a town and urban parish in the province of Pichincha, Ecuador. To find reviews, ratings, where to stay, and tourist information, go to the Puerto Quito trip planner.

Use the Route module to find suitable travel options from Cusco to Puerto Quito. On the 5th (Sat), you'll travel to Cartagena.
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Parks · Wildlife · Nature · Fun & Games

Cartagena, Colombia — 1 night

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Start off your visit on the 6th (Sun): contemplate the long history of Sanctuary of Saint Peter Claver, make a trip to Plaza Santo Domingo, and then examine the collection at Choco Museo. On your second day here, steep yourself in history at Las Bovedas, step into the grandiose world of Castillo de San Felipe de Barajas, and then contemplate in the serene atmosphere at Convent of Santa Cruz de la Popa.

To see ratings, more things to do, other places to visit, and tourist information, refer to the Cartagena trip itinerary tool.

Explore your travel options from Puerto Quito to Cartagena with the Route module. In November, plan for daily highs up to 37°C, and evening lows to 30°C. Finish your sightseeing early on the 7th (Mon) so you can fly to Guatemala City.
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Historic Sites · Museums

Guatemala City, Guatemala — 2 nights

The largest city in Central America and the country's capital, Guatemala City contains historic sights and modern businesses.
Explore Guatemala City's surroundings by going to Antigua (Volcán Pacaya, Casa Santo Domingo Museums, &more). There's still lots to do: learn about wildlife with up-close encounters at La Aurora Zoo, examine the collection at Museo Ixchel del Traje Indigena, don't miss a visit to Relief Map, and get engrossed in the history at Palacio Nacional.

To see where to stay, ratings, more things to do, and tourist information, refer to the Guatemala City itinerary maker tool.

Fly from Cartagena to Guatemala City in 7.5 hours. You'll gain 1 hour traveling from Cartagena to Guatemala City due to the time zone difference. Plan for little chillier temperatures traveling from Cartagena in November, with highs in Guatemala City at 27°C and lows at 17°C. Finish your sightseeing early on the 10th (Thu) so you can fly to San Miguel de Allende.
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Museums · Parks · Nature · Zoos & Aquariums
Side Trip

San Miguel de Allende, Mexico — 2 nights

A relatively small town in central Mexico, relaxed San Miguel de Allede offers an ideal setting for visitors in search of a bit of history and a great deal of photogenic architecture.
Start off your visit on the 11th (Fri): trot along with a tour on horseback. On the 12th (Sat), you'll have a packed day of sightseeing: take in the local highlights with Walking tours, relax and rejuvenate at some of the best spas, and then appreciate the extensive heritage of El Jardin.

To see other places to visit, maps, more things to do, and other tourist information, read our San Miguel de Allende route builder site.

Explore your travel options from Guatemala City to San Miguel de Allende with the Route module. Traveling from Guatemala City in November, plan for slightly colder nights in San Miguel de Allende, with lows around 12°C. You'll have a few hours on the 13th (Sun) to wrap things up before traveling home.
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Tours · Outdoors · Spas · Historic Sites

Province of Buenos Aires travel guide

4.1
Landmarks · Beaches · Churches
Unfolding around the capital city, the Province of Buenos Aires represents the country's hub of agricultural production. Though most visitors on vacation in the Province of Buenos Aires concentrate on exploring the memorable capital, the fertile plains surrounding the city provide a window into the country's rural way of life and gaucho culture. If you're looking for relaxation, a string of seafront resorts serve as quiet retreats by day and buzzing nightlife spots after dark. Well-planned tours of the Province of Buenos Aires rarely miss a chance to explore the area's quiet gaucho towns: old-fashioned settlements with cobblestone streets and appealing 19th-century architecture.
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Mexico travel guide

4.5
Ruins · Zipline · Beaches
Tailor-made for anyone seeking that traditional sun-and-sand experience, Mexico vacations allow visitors to explore nearly 10,000 km (6,200 mi) of picturesque coastlines. Idyllic beaches and favorable year-round weather aside, this diverse country with a rich pre-Colombian history allows tourists a chance to discover a fascinating cuisine, numerous archaeological sites, state-of-the-art museums, colonial-era haciendas, and outstanding examples of 21st-century architecture. Most visitors get to know the country by its cities, but if you want a well-rounded Mexico tour, spend some time exploring its jungles, cloud forests, Caribbean reefs, snowcapped volcanoes, vast deserts, and tranquil lagoons. Life is lived outdoors in Mexico, so wherever you go, don't forget to dine alfresco and stroll the country's colonial streets.
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