54 days in South America Itinerary

54 days in South America Itinerary

Created using Inspirock South America journey builder

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Route & dates

1
Bogota, Colombia
— 3 nights
2
Villa de Leyva, Colombia
— 2 nights
3
Medellin, Colombia
— 3 nights
4
Cartagena, Colombia
— 5 nights
5
Lima, Peru
— 3 nights
6
Arequipa, Peru
— 2 nights
7
Cusco, Peru
— 3 nights
8
Puno, Peru
— 3 nights
9
La Paz, Bolivia
— 3 nights
10
Uyuni, Bolivia
— 3 nights
11
Sucre, Bolivia
— 2 nights
12
Tupiza, Bolivia
— 1 night
13
Salta, Argentina
— 2 nights
14
Puerto Iguazu, Argentina
— 3 nights
15
Buenos Aires, Argentina
— 4 nights
16
Santiago, Chile
— 2 nights
17
Pichilemu, Chile
— 3 nights
18
Valparaiso, Chile
— 2 nights
19
Santiago, Chile
— 2 nights

3
nights
Bogota, Colombia

Bogota ©
Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Museum-lovers will appreciate Casa Museo Quinta de Bolivar and Casa de Moneda - Coleccion Numismatica del Banco de la Republica. Visit La Catedral Primada and Museo Santa Clara for their historical value. Explore Bogota's surroundings by going to Iglesia de Nuestra Senora de los Dolores (in Zipaquira) and Laguna de Guatavita (in Tierra Negra). And it doesn't end there: see the interesting displays at Museo Nacional de Colombia, hunt for treasures at Pasaje Rivas, look for gifts at Bta Capital, and savor the flavors at Plaza de Mercado de Paloquemao.

To see other places to visit, photos, reviews, and more tourist information, go to the Bogota online day trip planner.

Atlanta, USA to Bogota is an approximately 9-hour flight. Traveling from Atlanta in June, expect Bogota to be colder, temps between °F and °F. Finish your sightseeing early on the 4th (Thu) to allow enough time to drive to Villa de Leyva.

Things to do in Bogota

Museums Parks Outdoors

Side Trips

Iglesia de Nuestra Senora de los Dolores, Laguna de Guatavita
Highlights from your plan
Laguna de Guatavita ©
Laguna de Guatavita
Museo Nacional de Colombia ©
Museo Nacional de Colombia
Gold Museum (Museo del Oro) ©
Gold Museum (Museo del Oro)

2
nights
Villa de Leyva, Colombia

Villa de Leyva ©
Positioned away from major trade routes and exploitable resources, the colonial town of Villa de Leyva has been largely left alone--leaving a window into the 16th century that has become one of Colombia's most popular attractions.
Start off your visit on the 5th (Fri): get into the urban bustle at Alcaldia Villa de Leyva, take in the exciting artwork at Guadalupe Arte & Diseno, thentake an in-depth tour of Casa Museo Capitan Antonio Ricaurte, thenview the masterpieces at Devia Galeria, and finally see the interesting displays at Casa Museo Luis Alberto Acuna. On the next day, take in the architecture and atmosphere at Iglesia De Raquira, thendo a tasting at Vinedo Umana Dajud, thenidentify plant and animal life at Granja de Avestruces, and finally stop by Joyeria MORPHILIA.

For ratings, reviews, other places to visit, and tourist information, use the Villa de Leyva driving holiday tool.

You can drive from Bogota to Villa de Leyva in 2.5 hours. Another option is to take a bus. Cap off your sightseeing on the 6th (Sat) early enough to go by car to Medellin.

Things to do in Villa de Leyva

Museums Shopping Historic Sites

Side Trip

Iglesia De Raquira
Highlights from your plan
Casa Museo Luis Alberto Acuna ©
Casa Museo Luis Alberto Acuna
Casa Museo Capitan Antonio Ricaurte ©
Casa Museo Capitan Antonio Ricaurte
Iglesia De Raquira ©
Iglesia De Raquira

3
nights
Medellin, Colombia

Medellin ©
Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Get some cultural insight at Museo de Arte Moderno de Medellin and Museo Casa de la Memoria. You'll explore the less-touristy side of things at Parque Arvi and Cementerio Jardines Montesacro. Go for a jaunt from Medellin to Sabaneta to see Mayorca Mega Plaza about 32 minutes away. There's lots more to do: relax and rejuvenate at some of the best spas, admire the masterpieces at H by HDC, identify plant and animal life at Cerro El Volador, and engage your brain at Museo del Agua EPM.

For where to stay, photos, more things to do, and tourist information, use the Medellin vacation planner.

You can drive from Villa de Leyva to Medellin in 6.5 hours. Alternatively, you can fly; or take a bus. June in Medellin sees daily highs of °F and lows of °F at night. Wrap up your sightseeing on the 9th (Tue) early enough to travel to Cartagena.

Things to do in Medellin

Museums Wildlife Parks

Side Trips

Cementerio Jardines Montesacro, Mayorca Mega Plaza
Highlights from your plan
Museo Casa de la Memoria ©
Museo Casa de la Memoria
Parque Arvi ©
Parque Arvi
Museo de Arte Moderno de Medellin ©
Museo de Arte Moderno de Medellin

5
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Museum-lovers will get to explore Caribe Jewelry Museum & Factory and Casa Museo Rafael Nunez. Explore hidden gems such as Barrio Getsemani and Sanctuary of Saint Peter Claver. Venture out of the city with trips to Isla Baru (Aviario Nacional de Colombia & Playa Puntilla). And it doesn't end there: step into the grandiose world of Castillo de San Felipe de Barajas, get engrossed in the history at Museo del Oro Zenu, visit Centro Historico, and admire the landmark architecture of Cathedral Basilica of St. Catherine of Alexandria.

To see other places to visit, traveler tips, photos, and other tourist information, you can read our Cartagena online trip builder.

Getting from Medellin to Cartagena by flight takes about 4 hours. Other options: drive; or take a bus. In June, Cartagena is a bit warmer than Medellin - with highs of °F and lows of °F. Finish your sightseeing early on the 14th (Sun) to allow enough time to travel to Lima.

Things to do in Cartagena

Historic Sites Neighborhoods Museums

Side Trip

Isla Baru
Highlights from your plan
Templo de Santo Domingo ©
Templo de Santo Domingo
Aviario Nacional de Colombia ©
Aviario Nacional de Colombia
Sanctuary of Saint Peter Claver ©
Sanctuary of Saint Peter Claver

3
nights
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Head to Shopping Center Larcomar (Centro Comercial Larcomar) and Artdictosfor plenty of shopping. MALI - Museo de Arte de Lima and Museo Convento San Francisco y Catacumbas will appeal to museum buffs. And it doesn't end there: take a stroll through San Isidro, see the interesting displays at ChocoMuseo Kennedy, explore the world behind art at Museo MATE, and get engrossed in the history at AMANO, Museo Textil Precolombino.

To see photos, maps, more things to do, and tourist information, you can read our Lima online tour planner.

Traveling by flight from Cartagena to Lima takes 7 hours. Alternatively, you can drive; or do a combination of taxi and bus. Expect cooler weather when traveling from Cartagena in June: highs in Lima hover around °F, while lows dip to °F. Finish your sightseeing early on the 17th (Wed) to allow enough time to travel to Arequipa.

Things to do in Lima

Museums Historic Sites Neighborhoods
Highlights from your plan
San Isidro ©
San Isidro
Basilica y Monasterio de Santo Domingo ©
Basilica y Monasterio de Santo Domingo
MALI - Museo de Arte de Lima ©
MALI - Museo de Arte de Lima

2
nights
Arequipa, Peru

Arequipa ©
In an area dominated three imposing volcanoes, Arequipa vacations allow visitors to admire well-preserved colonial architecture in a dramatic setting.
Start off your visit on the 18th (Thu): view the masterpieces at Tristan del Pozo (Continental Bank Exhibition Gallery), thenexplore the world behind art at San Francisco Plaza, Church and Monastery, thenexamine the collection at Santa Catalina Monastery, and finally browse the exhibits of Arte Colonial.

For reviews, traveler tips, more things to do, and more tourist information, read Arequipa day trip planning website.

Fly from Lima to Arequipa in 3.5 hours. Alternatively, you can drive; or take a bus. Traveling from Lima in June, Arequipa is slightly colder at night with lows of °F. You will leave for Cusco on the 19th (Fri).

Things to do in Arequipa

Museums Shopping Historic Sites
Highlights from your plan
San Francisco Plaza, Church and Monastery ©
San Francisco Plaza, Church and Monastery
Santa Catalina Monastery ©
Santa Catalina Monastery

3
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Museum-lovers will get to explore Museo de Arte Precolombino and Museo Historico Regional. Your inner history buff will appreciate Tipon and Q'enqo. And it doesn't end there: make a short side trip with exploor, trot along with a tour on horseback, stroll through Santuario Animal de Cochahuasi, and take in the exciting artwork at Centro de Textiles Tradicionales del Cusco.

To find traveler tips, ratings, and other tourist information, read Cusco online journey planner.

Getting from Arequipa to Cusco by flight takes about 3 hours. Other options: drive; or take a bus. Traveling from Arequipa in June, Cusco is little chillier at night with lows of °F. Finish up your sightseeing early on the 22nd (Mon) so you can travel to Puno.

Things to do in Cusco

Museums Outdoors Tours
Highlights from your plan
exploor ©
exploor
Horseback Riding Tours
Q'enqo ©
Q'enqo

3
nights
Puno, Peru

Puno ©
Hugging the western tip of Lake Titicaca, Puno serves as a melting pot of indigenous and imported cultures, and makes a great base for explorations around the region.
Get outdoors at Taquile Island and Lake Umayo. Let the collections at Museo Carlos Dreyer and Museo de la Coca y Costumbres capture your imagination. Take a break from Puno with a short trip to Main Gate in Taquile Island, about 1h 30 min away. And it doesn't end there: explore the different monuments and memorials at Sillustani, take some stellar pictures from Mirador Ing. Eduardo Sanchez, stop by Luquina Chico, and take in the spiritual surroundings of Iglesia San Antonio.

You can plan Puno trip in no time by asking Inspirock to help create your itinerary.

You can fly from Cusco to Puno in 4.5 hours. Alternatively, you can drive; or take a bus. Traveling from Cusco in June, you can expect nighttime temperatures to be a bit cooler in Puno, with lows of °F. Cap off your sightseeing on the 25th (Thu) early enough to go by car to La Paz.

Things to do in Puno

Historic Sites Nature Parks

Side Trip

Main Gate
Highlights from your plan
Iglesia San Antonio ©
Iglesia San Antonio
Taquile Island ©
Taquile Island
Museo Carlos Dreyer ©
Museo Carlos Dreyer

3
nights
La Paz, Bolivia

La Paz ©
Take a moment to catch your breath as you commence your holiday in La Paz.
Appreciate the collections at National Museum of Ethnography and Folklore and Museum of Musical Instruments - Museo Instrumentos Musicales de Bolivia. Get outdoors at La Paz Golf Club and Scree Rush. Step out of La Paz to go to El Alto and see El Alto Market, which is approximately 42 minutes away. And it doesn't end there: take in the architecture and atmosphere at Catedral Basilica Menor de Nuestra Senora de la Paz, take a stroll through Sopocachi, stop by Green Hands, and see the interesting displays at Bolivian Drink Museum.

To find where to stay, other places to visit, reviews, and other tourist information, refer to the La Paz sightseeing app.

You can drive from Puno to La Paz in 4 hours. Alternatively, you can take a bus. Due to the time zone difference, you'll lose 1 hour traveling from Puno to La Paz. When traveling from Puno in June, plan for little chillier days and about the same nights in La Paz: temperatures range from °F by day to °F at night. Finish your sightseeing early on the 28th (Sun) so you can travel to Uyuni.

Things to do in La Paz

Outdoors Winter Sports Wildlife

Side Trip

El Alto Market
Highlights from your plan
Scree Rush ©
Scree Rush
National Museum of Ethnography and Folklore ©

3
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Visiting Isla Incahuasi and Salar de Uyuni will get you outdoors. Museo de la Llama y la Sal and Museo Arquecologia y Antropologico de los Andes Meridionales are good opportunities to explore the local culture. Spend the 29th (Mon) wandering through the wild on a nature and wildlife tour. There's more to do: get to know the fascinating history of Avenida Ferroviaria.

For more things to do and other tourist information, go to the Uyuni tour app.

Traveling by flight from La Paz to Uyuni takes 4 hours. Alternatively, you can drive; or do a combination of bus and taxi. While traveling from La Paz, expect little chillier days and a bit warmer nights in Uyuni, ranging from highs of °F to lows of °F. On the 2nd (Thu), you're off to Sucre.

Things to do in Uyuni

Outdoors Wildlife Tours

Side Trip

Museo de la Llama y la Sal
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi
Nature & Wildlife Tours

2
nights
Sucre, Bolivia

Sucre ©
The constitutional capital of Bolivia, Sucre has a well-preserved historic center, with many buildings dating back to the city's founding in the 16th century.
Start off your visit on the 3rd (Fri): pause for some serene contemplation at Iglesia Nuestra Senora de La Merced, thenstop by Inca Pallay Shop, thentake an in-depth tour of House of Liberty Museum - Casa de la Libertad, and finally take in the architecture and atmosphere at Basilica de San Francisco.

For reviews, more things to do, and tourist information, go to the Sucre day trip planning website.

Getting from Uyuni to Sucre by flight takes about 6.5 hours. Other options: drive; or do a combination of taxi and bus. While traveling from Uyuni, expect much hotter days and about the same nights in Sucre, ranging from highs of °F to lows of °F. On the 4th (Sat), wrap the sightseeing up by early afternoon so you can drive to Tupiza.

Things to do in Sucre

Historic Sites Museums Shopping
Highlights from your plan
Iglesia Nuestra Senora de La Merced ©
Iglesia Nuestra Senora de La Merced
Basilica de San Francisco ©
Basilica de San Francisco

1
night
Tupiza, Bolivia

The southwestern mining town of Tupiza, near the Argentine border, reminisces of the wild west, and is supposedly the place where Butch Cassidy and the Sundance Kid faced their demise after a long string of bank robberies.
Kick off your visit on the 5th (Sun): get outside with Outdoor Activities and then take in the dramatic natural features at Puerta del Diablo.

To find traveler tips, photos, where to stay, and other tourist information, go to the Tupiza online attractions planner.

Drive from Sucre to Tupiza in 6 hours. Alternatively, you can fly; or take a bus. Cap off your sightseeing on the 5th (Sun) early enough to travel to Salta.

Things to do in Tupiza

Outdoors Tours Nature
Highlights from your plan
Climbing Tours
Puerta del Diablo ©
Puerta del Diablo

2
nights
Salta, Argentina

Salta ©
Salta boasts a vibrant social life and array of informative museums appealing to visitors looking for a memorable cultural experience.
Discover out-of-the-way places like Museo Guemes and Alemania. Take a break from the city and head to Quebrada de San Lorenzo and Reserva del Huaico. The adventure continues: pause for some serene contemplation at Iglesia Nuestra Senora de La Candelaria de La Vina, get a new perspective on nature at MAAM - Museo de Arqueologia de Alta Montana de Salta, examine the collection at Museo Pajarito Velarde, and contemplate in the serene atmosphere at Cathedral of Salta.

To see ratings, other places to visit, traveler tips, and tourist information, read our Salta trip planner.

Getting from Tupiza to Salta by car takes about 7.5 hours. Other options: do a combination of car and flight. You'll lose 1 hour traveling from Tupiza to Salta due to the time zone difference. Expect a daytime high around °F in July, and nighttime lows around °F. Finish your sightseeing early on the 8th (Wed) so you can travel to Puerto Iguazu.

Things to do in Salta

Parks Nature Museums

Side Trips

San Lorenzo, Ojo de Mar
Highlights from your plan
Museo Guemes ©
Museo Guemes
Basilica Menor San Francisco ©
Basilica Menor San Francisco

3
nights
Puerto Iguazu, Argentina

Puerto Iguazu ©
The gateway to a national park inscribed on the World Heritage List, growing Puerto Iguazu sits on the confluence of two major rivers near the border with Paraguay and Brazil.
Start off your visit on the 9th (Thu): make a trip to Plaza San Martin, stroll through Sendero Macuco, and then take in the dramatic scenery at Cataratas del Iguazu - Lado Argentino. Get ready for a full day of sightseeing on the next day: look for gifts at Duty Free Shop Puerto Iguazu, thenadmire the sheer force of Salto Bernabe Mendez, thensteep yourself in history at La Aldea Fortin M'Borore, and finally look for all kinds of wild species at Jardin de los Picaflores.

To find other places to visit, maps, ratings, and more tourist information, read our Puerto Iguazu visit planner.

You can fly from Salta to Puerto Iguazu in 4.5 hours. Other options are to drive; or take a bus. Traveling from Salta in July, Puerto Iguazu is somewhat warmer at night with lows of °F. Wrap up your sightseeing by early afternoon on the 11th (Sat) to allow enough time to travel to Buenos Aires.

Things to do in Puerto Iguazu

Parks Nature Wildlife

Side Trip

Salto Bernabe Mendez
Highlights from your plan
Salto Bernabe Mendez ©
Salto Bernabe Mendez
Jardin de los Picaflores ©
Jardin de los Picaflores
Puerto Iguazu ©
Puerto Iguazu

4
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Explore hidden gems such as Catedral de San Isidro and Museo Nacional De Arte Decorativo. Get outdoors at Parque 3 de Febrero and Peru Beach. Explore the numerous day-trip ideas around Buenos Aires: Basilica de Lujan (in Lujan) and Reserva Natural Urbana (in Castelar). There's lots more to do: pause for some serene contemplation at Basilica del Santisimo Sacramento, step into the grandiose world of Palacio de Aguas Corrientes, take a stroll through Puerto Madero, and appreciate the extensive heritage of Calle Defensa.

To see traveler tips, photos, more things to do, and other tourist information, read our Buenos Aires trip planner.

You can fly from Puerto Iguazu to Buenos Aires in 4 hours. Other options are to drive; or take a bus. In July, Buenos Aires is a bit cooler than Puerto Iguazu - with highs of °F and lows of °F. Finish your sightseeing early on the 15th (Wed) to allow enough time to travel to Santiago.

Things to do in Buenos Aires

Historic Sites Neighborhoods Parks

Side Trips

Basilica de Lujan, Catedral de San Isidro, Reserva Natural Urbana, Peru Beach
Highlights from your plan
Catedral de San Isidro ©
Catedral de San Isidro
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Basilica del Santisimo Sacramento ©
Basilica del Santisimo Sacramento

2
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Kick off your visit on the 16th (Thu): get engrossed in the history at Museo Historico Nacional, thenwander the streets of Isidora Goyenechea, and then contemplate the long history of Centro Cultural Palacio de la Moneda y Plaza de la Ciudadania. On the next day, view the masterpieces at Galeria Arte Tierra, thentake in the awesome beauty at San Cristóbal Hill, thencontemplate in the serene atmosphere at Santuario de la Inmaculada Concepcion, and finally don't miss a visit to Grand Santiago Tower.

To see where to stay, ratings, traveler tips, and more tourist information, go to the Santiago itinerary planner.

Fly from Buenos Aires to Santiago in 6 hours. Alternatively, you can drive; or take a bus. The time zone changes from Argentina Standard Time to Chile Standard Time, which is usually a -1 hour difference. Finish your sightseeing early on the 17th (Fri) to allow enough time to travel to Pichilemu.

Things to do in Santiago

Shopping Neighborhoods Museums
Highlights from your plan
Isidora Goyenechea ©
Isidora Goyenechea
San Cristóbal Hill ©
San Cristóbal Hill
Museo Historico Nacional ©
Museo Historico Nacional

3
nights
Pichilemu, Chile

Pichilemu ©
A beach resort city in the center of the country, Pichilemu has earned the title of Chile's "Surf Capital," gaining international acclaim as the host of numerous competitions.
On the 18th (Sat), do a tasting at Vina Las Ninas, thenlook for gifts at Vinonauta, thensteep yourself in history at Estacion de Ferrocarriles de Colchagua, and finally see the interesting displays at Museo El Huique. Keep things going the next day: stroll through Playa Punta de Lobos, explore the striking landscape of Reserva Nacional Laguna Torca, and then examine the collection at Museo del Nino Rural.

To see traveler tips, maps, and other tourist information, use the Pichilemu trip itinerary planning site.

Traveling by car from Santiago to Pichilemu takes 3 hours. In July, plan for daily highs up to °F, and evening lows to °F. Wrap up your sightseeing by early afternoon on the 20th (Mon) to allow time for travel to Valparaiso.

Things to do in Pichilemu

Parks Outdoors Beaches

Side Trips

Santa Cruz, Reserva Nacional Laguna Torca
Highlights from your plan
Reserva Nacional Laguna Torca ©
Reserva Nacional Laguna Torca
Playa Punta de Lobos ©
Playa Punta de Lobos
Playa La Puntilla ©
Playa La Puntilla

2
nights
Valparaiso, Chile

Valparaiso ©
Navigating through a maze of colorful streets winding up and down steep hills remains an integral part of any Valparaiso tour.
Start off your visit on the 20th (Mon): view the masterpieces at Galeria Municipal de Arte. On your second day here, delve into the distant past at Moai, examine the collection at Corporacion Museo de Arqueologia e Historia Francisco Fonck, appreciate the extensive heritage of Paseo Gervasoni, thenget engrossed in the history at Museo Mirador Lukas, thenget to know the fascinating history of Paseo Yugoslavo, and finally admire the masterpieces at Palacio Baburizza.

For maps, ratings, and more tourist information, use the Valparaiso holiday planning tool.

Getting from Pichilemu to Valparaiso by car takes about 3.5 hours. Traveling from Pichilemu in July, plan for somewhat warmer nights in Valparaiso, with lows around °F. Finish up your sightseeing early on the 22nd (Wed) so you can go by car to Santiago.

Things to do in Valparaiso

Museums Historic Sites Shopping

Side Trip

Vina del Mar
Highlights from your plan
Palacio Baburizza ©
Palacio Baburizza
Paseo Gervasoni ©
Paseo Gervasoni

2
nights
Santiago, Chile

Santiago ©
Start off your visit on the 23rd (Thu): look for gifts at Patio Bellavista, step into the grandiose world of Castillo Hidalgo, and then take in the architecture and atmosphere at San Francisco Church.

For maps, reviews, traveler tips, and more tourist information, you can read our Santiago trip site.

Drive from Valparaiso to Santiago in 1.5 hours. Alternatively, you can take a bus. On the 24th (Fri), you'll have the morning to explore before heading back home.

Things to do in Santiago

Shopping Historic Sites
Highlights from your plan
Patio Bellavista ©
Patio Bellavista
San Francisco Church ©
San Francisco Church
Castillo Hidalgo ©
Castillo Hidalgo

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